Saturday, September 13, 2025, is packed with thrilling sports action! From major college football battles featuring top-ranked teams to a classic Yankees-Red Sox rivalry matchup, and a high-stakes boxing event, there’s something for every sports fan and bettor. This article provides a comprehensive guide to the day’s top games, best bets, and odds, leveraging expert analysis from the SportsLine Projection Model and CBS Sports experts to help you make informed decisions.
Week 3 of the college football season brings several high-profile matchups with significant betting implications. Keep an eye on key games like Clemson vs. Georgia Tech, Georgia vs. Tennessee, and South Florida vs. Miami. In MLB, the Yankees and Red Sox face off in a crucial game with Wild Card implications. Plus, boxing fans can look forward to Canelo Alvarez vs. Terence Crawford. Let’s dive into the details!
College Football Week 3: Top Games and Upset Alerts
Week 3 of the college football season features several compelling matchups with ranked teams facing off, creating ample opportunities for upsets and intriguing betting scenarios. With 23 ranked teams in action, including six games featuring two top-25 teams, the stakes are high. After a Week 2 filled with surprises, let’s look at some games to watch.
Clemson at Georgia Tech (12 p.m. ET, ESPN): No. 12 Clemson, a slight 2.5-point road favorite, visits Georgia Tech. Clemson struggled early against Troy last week, requiring a second-half rally. This game could be an upset alert as the Yellow Jackets look to capitalize on Clemson’s vulnerabilities.
Georgia at Tennessee (3:30 p.m. ET, ABC): No. 6 Georgia is a 3.5-point road favorite against No. 15 Tennessee. Historically, Tennessee has struggled against Kirby Smart’s Georgia defenses. The Volunteers haven’t scored more than 17 points in their last four meetings with the Bulldogs, making Georgia a solid pick.
South Florida at Miami (4:30 p.m. ET, The CW Network): No. 18 South Florida, after upsetting Boise State and Florida, faces No. 5 Miami. Miami is a heavy favorite at -17.5, but South Florida has proven capable of pulling off upsets. This game will test Miami’s dominance and South Florida’s momentum.
SEC Underdog Watch (7 p.m. and 7:30 p.m. ET): Three SEC teams—Arkansas, Florida, and Texas A&M—are 6.5-point road underdogs against Ole Miss, LSU, and Notre Dame, respectively. These night games offer high-profile upset potential. Keep an eye on these contests for exciting betting opportunities.
No. 6 Georgia at No. 15 Tennessee: Best Bets and Expert Picks
The clash between No. 6 Georgia and No. 15 Tennessee is one of the most anticipated games of the day. The line has shifted significantly, with Georgia initially favored by 7.5 points, now down to 3.5 at some sportsbooks. Georgia has been dominant in its first two games, scoring a combined 73 points against Marshall and Austin Peay. Tennessee nearly matched that with 72 points against East Tennessee State.
SportsLine college football expert Thomas Casale believes the line is too low, stating, “I also think Kirby Smart has been holding things back the first couple of games, knowing he faced Tennessee in Week 3. Look for QB Gunner Stockton to be much more aggressive this week with Tennessee down its two starting corners.”
The SportsLine Inside the Lines team suggests taking Over 50.5 points (-109), citing the potential for an aggressive offensive game from both sides. Given the offensive capabilities and defensive vulnerabilities, this game promises to be a high-scoring affair.
USC at Purdue: Trojans’ Road Test and High-Scoring Potential
No. X USC, the highest-scoring team in the nation, faces Purdue in their first road game of the season. USC has been an offensive juggernaut, scoring 73 points against Missouri State and 59 against Georgia Southern. Purdue, however, will be looking to put up a fight at home.
SportsLine’s Inside the Lines team gives an A grade to Over 59.5 points (-109) in this Big Ten contest, with the average score coming out to 63 points across 10,000 simulations. The Trojans’ explosive offense combined with Purdue’s vulnerabilities makes this a likely high-scoring matchup.
SportsLine expert Jake Fetner advises laying the points with USC, noting, “Purdue didn’t have an FBS win last season and has a new roster. While they should be improved this season, they were 0-5 SU and ATS in FBS home games last season with an average score of 9-41. Going from Ball State and Southern Illinois to USC is quite the step up in competition, and USC has shown they are explosive on offense.”
MLB: Yankees at Red Sox – A Crucial Rivalry Game
The Yankees and Red Sox face off in a pivotal game with significant AL Wild Card implications. The Yankees currently hold the top Wild Card spot, with the Red Sox trailing by 1.5 games. After the Yankees’ 4-1 victory on Friday, this Saturday matchup is crucial.
The Yankees are sending ace Max Fried (16-5, 3.02 ERA) to the mound, while the Red Sox counter with Brayan Bello (11-6, 3.12 ERA). Despite the strong pitching matchup, the Inside the Lines team recommends taking Over 8.5 runs (-114) at Fenway, with simulations hitting that Over in 64.6% of cases.
Given the rivalry, the stakes, and the potential for offensive fireworks, this game is a must-watch for baseball fans and bettors alike.
Looking Ahead: Eagles at Chiefs – A Super Bowl Rematch
Looking ahead to Sunday, the Eagles and Chiefs will rematch in Week 2. The Chiefs, seeking to avenge their Super Bowl defeat, are also trying to avoid an 0-2 start. Kansas City is a rare home underdog in the Patrick Mahomes era, with the Eagles favored by 1.5 points.
SportsLine expert R.J. White anticipates a strong performance from the Eagles defense, stating that it “should play better with Jalen Carter back on the field, and the offense gets to face a Chiefs defense that was knocked around by Greg Roman in Week 1.”
The Inside the Line team suggests betting Under 47 points (-110), expecting a defensive battle. This Super Bowl rematch promises high intensity and strategic gameplay.
Final Thoughts and Key Takeaways
Saturday, September 13, 2025, offers a plethora of exciting sports events and betting opportunities. From major college football matchups to a classic Yankees-Red Sox rivalry and a high-profile boxing event, there’s something for every sports fan.
Key games to watch include Clemson vs. Georgia Tech, Georgia vs. Tennessee, South Florida vs. Miami, and Yankees vs. Red Sox. Top betting picks include Over 50.5 points in Georgia vs. Tennessee and Over 59.5 points in USC vs. Purdue. Looking ahead, the Eagles vs. Chiefs Super Bowl rematch is set to be a thrilling contest.
By leveraging expert analysis and projection models, sports fans and bettors can make informed decisions and enjoy a day filled with exciting sports action. Stay tuned for more updates and insights as the games unfold!
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